Harden's television credits include the political drama series The Newsroom, the medical drama series Code Black, the legal thriller series How to Get Away with Murder, and the Apple TV+ drama series The Morning Show. She returned to Broadway in 2009 as Veronica in God of Carnage, with her performance earning her the Tony Award for Best Actress in a Play. Harden made her Broadway debut in 1993, starring in Angels in America, for which she was nominated for a Tony Award for Best Featured Actress in a Play.
Her other notable film credits include The First Wives Club (1996), Flubber (1997), Space Cowboys (2000), Mona Lisa Smile (2003), and the Fifty Shades film trilogy. She received a second Academy Award nomination for her performance as Celeste Boyle in the drama film Mystic River (2003). For her portrayal of artist Lee Krasner in the 2000 biographical film Pollock, she won the Academy Award for Best Supporting Actress. In 1986, she appeared in her first film role, with her breakthrough coming in the 1990 Coen brothers-directed Miller's Crossing. Born in La Jolla, California, Harden began her acting career appearing in several television programs throughout the 1980s.
